could be a bit high of a dose if uve never done opiates before. you never know could be allergic or very sensitive 2 opiates. id say if its your first time stay at about 20-25 since you are a bigger guy. next time up the dose 1 or 2 percs. be carefull though thats alot of acetiminophene. i wouldnt eat 2 many w/o doing an extraction.
I wouldn't worry about a high dose of oxy as much as the acetaminophen (APAP) that's in each of those pills. There are 500mg of APAP per pill so keep in mind that OD levels of APAP are around 3500 - 4000mg. I'd say start with 15 - 20mg if you don't use opiates very much.