For those who have troubles with salvia from consumption to horticulture, you might wanna check out this site, very excellent http://www.sagewisdom.org i also recommend joining the Salvia Divinorum Observer group for recent studies and news articles SALVIA USED TO EVADE DRUG PARAPHERNALIA LAWS http://tinyurl.com/asew2
check these out dude PHARMACOKINETICS OF SALVINORIN A IN NONHUMAN PRIMATES TITLE: Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. AUTHORS: Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE. JOURNAL: Synapse. 58(3): 208-210 [2005]. ABSTRACT: Salvinorin A, a potent hallucinogen isolated from the leaves of Salvia divinorum, has gained popularity among adolescents in the USA. No detailed study of the pharmacokinetics has been conducted in vivo. The present study investigates the in vivo pharmacokinetics of salvinorin A (0.032 mg/kg, i.v. bolus) in rhesus monkeys (n = 4, 2 male, 2 female). The elimination t(1/2) was rapid (56.6 +/- 24.8 min) for all subjects. Pharmacokinetic differences (distribution t(1/2), elimination t(1/2), and AUC) were observed between males and females, suggesting potential sex differences in its pharmacologic effects. Salvinorin B, the presumed major metabolite, is observed to accumulate ex vivo; however, in this study it never reached the limit of detection. Synapse subscribers can access this paper from the journal's website. It will be added to the SDRIC website in about a week. MISSOURI BILL SEEKS TO MAKE SALVIA DIVINORUM ILLEGAL House Bill 165 in Missouri seeks to add Salvia divinorum to that state's list of Schedule I controlled substances. The bill only mentions Salvia divinorum. Curiously, it does not mention its primary active constituent, salvinorin A. http://www.house.state.mo.us/bills051/biltxt/intro/HB0165I.htm First Louisiana, now these asswipes? TWO NEW COMPOUNDS IDENTIFIED IN SALVIA DIVINORUM TITLE: Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum. AUTHORS: Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. JOURNAL: Organic Letters. 7(14): 3017-3020 (2005). (unfortunately the link is unavailable) NEW SALVINORIN DERIVATIVE IS SEVEN TIMES MORE POTENT THAN SALVINORIN A http://dx.doi.org/10.1016/j.bmcl.2005.05.048 At least its good news.
