does mixing different kinds of weed into a bowl mess you up? is it better, worse? more anxiety? it just seems like different kinds of cannabanoids mixing and clashing wouldn't be fun...is this true?
different cannabinoids? not really. they're all the same ingredients. any compositional differences between strains are pretty insignificant. i often have 2-3 strains in the same bag. sometimes i smoke one, sometimes i mix them all up. to be honest, there's no difference. although, some strains are better than others and you'll likely notice a better high by closely comparing them in this manner. and, of course, there's nothing dangerous about doing this...
I notice a difference. In most Sativa buds there is a lack of chemicals like CBD and CBN, that cause some distinct body effects. I don't really care what strains I am smoking or if I mix them, but I always notice a difference between different buds. The taste can also get a little funky if you mix strong tasting nugs.