GANESHA- where is this RC?

Discussion in 'Synthetic Drugs' started by raoul duke420, Mar 3, 2008.

  1. raoul duke420

    raoul duke420 Member

    Messages:
    274
    Likes Received:
    0
    Sure would like to find an rc source that has this available. down to trade sources if anyone can help me out. Thanks - peace


    Ganesha - 2,5-DIMETHOXY-3,4-DIMETHYLAMPHETAMINE

    DOSAGE: 20 - 32 mg.

    DURATION: 18 - 24 h.

    QUALITATIVE COMMENTS: (with 24 mg) There was a slow buildup to a
    ++ or more over the course of about three hours. Extremely tranquil, and no hint of any body toxicity whatsoever. More than tranquil, I was completely at peace, in a beautiful, benign, and placid place. There was something residual that extended into the sleep period, and was possibly still there in the morning. Probably I was simply tired from an inadequate sleep.

    (with 32 mg) A rapid and full development. Lying down with music, the eyes-closed visuals were quite something. There was sudden awareness of a potential toe cramp which I possibly exaggerated, but it kept spinning itself into my awareness, and somehow locked in with my visual imagery. It was not easy to keep the visual/somatic/ cognitive worlds in their proper places. The almost-cramp went away and I forgot about it. There was a back spasm somewhere in this drama, and it really didn't matter either. This dosage may be a bit much for good housekeeping, though! Towards the end of the experiment, I looked at a collection of photos from a recent trip to Europe, and the visual enhancement was wonderful. A rolling
    +++ .

    EXTENSIONS AND COMMENTARY: This compound was the seventh of the ten possible Classic Ladies. I have mentioned the concept already under the discussions on ARIADNE. This is the teutonic replacement of each of the distinguishable hydrogen atoms of DOM with a methyl group. The findings with GANESHA were a total surprise. The extension of a hydrogen in the 3-position of DOM with a methyl group should have a minor influence on its steric association with whatever receptor site might be involved. A much greater impact might come not from the size of the group but from its location. This, coupled with a full order of magnitude of decrease in potency, seemed to call for an involvement of that particular position as being one that is affected by metabolism. And since the activity is decreased, the obvious role is in the blocking of the metabolic promotion of DOM-like things to active intermediates.

    The remarkable point being emphasized here is that the placement of a dull methyl group at a dull position of the DOM molecule actually inactivated (for all intents and purposes) the activity of DOM. It is not the presence of the methyl that has decimated the potency, but the removal of the hydrogen atom.

    How can such a hypothesis be explored? A historic premise of the medicinal chemist is that if a structure gives an unusual response in a receptor, vary it slightly and see how the response varies. This is exactly the principle that led to the ten Classic Ladies, and with this particular Lady (who actually turned out to be a gentleman), the same concept should hold. There are two involved methyl groups in GANESHA, one at the 3-position and one at the 4-position. Why not homologate each to an ethyl group, and as a wrap up make both of them into ethyl groups. Look at the differences along two lines of variation; the effects of the homologation of the 3- and 4-positions, coupled with the effects of the homologation intrinsic in the comparison of the two-carbon chain of the phenethylamine with the three-carbon chain of the amphetamine.

    There are thus six compounds involved in such a study. And they have been named (as have all the other GANESHA analogues) in accordance with the collective carbon inventory in and about these two ring positions. The first two compounds are related to DOET and to
    2C-E. Maintain the methyl group at the 3-position but homologate the 4-position to an ethyl. The ring pattern would become 2,5-dimethoxy-4-ethyl-3-methyl, and the phenethylamine and amphetamine would be called 2C-G-12 and G-12 respectively (a one carbon thing, the methyl, at position-3 and a two carbon thing, an ethyl, at position-4). Reversal of these groups, the 3-ethyl homologues of 2C-D and DOM would thus become 2C-G-21 and G-21. And, finally, the diethyl homologues would be 2C-G-22 and G-22. In each of these cases, the paired numbers give the lengths of the chains at the two positions, the 3- and the 4-positions that are part of the GANESHA concept. And this code is easily expandable to longer things such as 2C-G-31 and 2C-G-41, which would be the 3-propyl-4-methyl, and the 3-butyl-4-methyl homologues, resp.

    Unfortunately, these six initially proposed compounds have so far resisted all logical approaches to synthesis, and are at present still unknown. What has been successfully achieved, the building up of a big bulky hydrocarbon glob at these positions, has rather unexpectedly led to a remarkable enhancement of potency. As with all true exploration into areas of the unknown, the deeper you get, the less you understand.
     
  2. omshiva

    omshiva Member

    Messages:
    115
    Likes Received:
    0
    ganesha is way too long.
     
  3. Schwag

    Schwag Member

    Messages:
    52
    Likes Received:
    0
    I would also be interested in trying this drug. The sedative psychedelic effects intrigue me. Unfortunately Raoul, I don't think anybody has it for sale. You could do a custom synthesis, though it's expensive.
     
  4. podious

    podious Member

    Messages:
    272
    Likes Received:
    0
  5. DerickTheDude

    DerickTheDude Member

    Messages:
    1
    Likes Received:
    0
    My guy does that, if you have a 2c-b source I'd be down to swap emails.
     
  6. Meretrix

    Meretrix Member

    Messages:
    656
    Likes Received:
    1
    I haven't heard much about this really, but it sounds amazing. I would also be quite interested in this...
     
  7. Geneity

    Geneity self-proclaimed advocate

    Messages:
    6,637
    Likes Received:
    7
    Thought it was DOM at first. I've never heard of or seen anwywhere selling this stuff.
     
  8. raoul duke420

    raoul duke420 Member

    Messages:
    274
    Likes Received:
    0
    Somehow I find it hard to believe the 16 year old with one post has the hook on this hard to find rc, thanks though bro, If you really want to trade then hit me up
     
  9. vibra

    vibra Member

    Messages:
    42
    Likes Received:
    0
    Interesting!
    I'm sure this will be available on the RC market in the near future.
     
  10. gecko7

    gecko7 Member

    Messages:
    19
    Likes Received:
    0
    i dont think so... at least not in the near future..
    the rc market is somewhat slow in offering new stuff..
    which was the news in the market last year?
    ther were the 4-substit tryptamines, new batches mdpv & desoxypipradol, the diphenyl-prolinol thing, mephedrone,IAP,eth-cath, and that syntetich cannabinoid
    br-dfly was also a new entry(feel free to correct me if im wrong)

    most of those are very simple substitutions(4-aco, 4-ho) and
    some of those were new batches of things already appeared some years ago..so, only a few are revolutionary new things

    the other reseaarch chems, like 2c-stuff, DO-X , some 2ct-stuff, 5-meo-things, betaketo-methylenedioxy-analogues... those were around for years now...

    those exotic stuff needs custom synth(3000+$) and the vendor has to be sure that researchrs will buy it.

    yeah, for sure, i am too curious about those things(you know.. a psychedelich drug named 'ganesha' !!! yuck! wow!LOL!!) like aleph, escaline, 3c-things, 5-meo-AET, 7-F-AMT...and so on
     
  11. Egor

    Egor Member

    Messages:
    91
    Likes Received:
    0
    2c-g (the phenethylamine counterpart) was available for a short time, but I have never seen ganesha available
     
  12. AuraithX

    AuraithX Member

    Messages:
    107
    Likes Received:
    0
    So GANESHA has an extra methyl added to DOM's structure.

    methyl groups usually just affect potency, no?

    So, a longer lasting DOM? no thanks.
     
  13. Geneity

    Geneity self-proclaimed advocate

    Messages:
    6,637
    Likes Received:
    7
    2C-G is supposed to be pretty visually absent
     
  14. Schwag

    Schwag Member

    Messages:
    52
    Likes Received:
    0
    I was thinking Ganesha would be more like a really long version of 4-AcO-DMT, than DOM. I personally find 4-AcO-DMT to be very sedative and relaxing. When Shulgin mentioned about Ganesha being sedative and relaxing in his book, it reminded me of 4-AcO-DMT. They're not chemically related though, so I could be way off.
     
  15. Geneity

    Geneity self-proclaimed advocate

    Messages:
    6,637
    Likes Received:
    7
    4-Acetoxy-DMT undergoes direct conversion to Psilocin in the body.
     
  16. Schwag

    Schwag Member

    Messages:
    52
    Likes Received:
    0
    I know this, I just think the sedative aspects might provide for a similar experience. By the way, I think many would argue it is not a direct conversion.
     
  17. raoul duke420

    raoul duke420 Member

    Messages:
    274
    Likes Received:
    0
    I am thinking that some doc sounds a bit better , kinda hard to find it seems though
     
  18. Geneity

    Geneity self-proclaimed advocate

    Messages:
    6,637
    Likes Received:
    7
    It's probably not quite the same as 4-phosphoroxy-DMT that's in mushrooms.
     

Share This Page

  1. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
    By continuing to use this site, you are consenting to our use of cookies.
    Dismiss Notice