anyone ever heard of phenibut, and if so, what do you know about it? i gathered some information about it on google, but still am unsure of what is and is not known about it - but it seems it HAS been studied.... a friend had me order some for him online. i didn't deny him, its his choice to do it or not, but it sounds fishy to me. primarily i'd like to find out about studies in humans. i have seen information related to effects in animals, but thats a bit different. i'd also like more concrete information about typical clinical doses, if that information is out there. i've found a very rough guideline, but i'm interested in second opinions in matters like these. finally, if anyone has any personal knowledge, experience, anecdotes related specifically to administration of phenibut in humans and the potential psychoactive effects of said substance, please help enlighten me many thanks in advance to anyone with any knowledge of this enigmatic substance.
Here I went to wikipedia, and I don't know if you already looked or not but here's the link. http://en.wikipedia.org/wiki/Phenibut Heres what I've pulled out that might be of interest to you and your friend. It was developed in Soviet Union, and there it has been used clinically since the 1960's for a range of purposes. Phenibut has both nootropic and anxiolytic (anxiety-reducing) properties, and it is commonly compared to diazepam (Valium), baclofen, and piracetam, and it has similarities to and differences from all of these substances. Phenibut has anticonvulsant activity against some drugs or conditions, but not others. It also potentiates the action of some other anticonvulsant drugs, and has been used to treat patients with epilepsy. Phenibut has been reported to reduce motion sickness, and used in the treatment of alcohol and morphine withdrawal. One study indicated that phenibut increased resistance to heat stress and improved working capacity in humans. Some studies indicate that phenibut has anti-arrhythmic properties in humans . It also has other cardioprotective properties. Phenibut has low acute toxicity. Reported LD50s (dose required to kill 50% of laboratory animals) are 900 mg/kg i.p. in mice, 700 mg/kg i.p. in rats, and 1000 mg/kg in rats (method of administration not given). Chronic administration of 50 mg/kg did not have teratogenic effects in rats. In clinical studies, no signs of toxicity have been reported, and side effects are few. Some report drowsiness, but this effect is not nearly as likely or severe as with benzodiazepines Tolerance develops to many of the effects of phenibut, although it is reported that it does not develop to the nootropic effect. The first signs of tolerance may be seen within as little as five days. For this reason, it is commonly used for one to two week periods, or dosage is increased by 25-30% after two weeks. This makes phenibut ideal for short periods of stress or anxiety, but not ideal for chronic use. It is possible that taking only one dose daily may partially reduce the development of tolerance. Yeah, thats the copy and pasted version of what it thought would be relavent to you, and good luck with all your adventures through life.