So what's the deal with DXM and MAOI's?

I read that you should wait for like 2 weeks after stopping an MAOI before you take DXM.

Is that because they build up in your body? What if you wanted to take a very mild MAOI (like passion flower) as a one time thing; how long should you wait to take DXM? What happens if you mix the two?

Also, how long do I need to wait after taking DXM to take something containing passion flower, or another mild MAOI?

And one more question, if anyone knows... is it dangerous to take 5-htp with a small amount of DXM? What about taking 100mg of 5-htp the day after a DXM trip?

 

Im not sure about maois and dxm but i know that ssris and dxm can lead to serotonin syndrome. Hopefully someone else can asnwer you about the effects of maois and dxm together.

As for 5htp and dxm, it should be safe. Ive known of people taking e with 5htp and they are fine. I know e and dxm arent the same but 5htp is a vitamin so you should be safe.

 

5htp is not a vitamin, but close enough i guess. and i actually remember reading that taking 5htp while your taking dxm its bad for you. i'll have to find the article to get you the specifics, but it has to do with what they do and how they interact in the brain. as for mixing maois and dxm its supposedly fatal.
edit: yeah i couldnt find the article about dxm and 5htp. but i remember reading it when i had some 5htp and was trying to mix the two. i did it a few times without anything bad happening but after i read the article i didnt anymore. it said something about when used at the same time it can cause bad reactions, but i dont know. id do it before hand if anything, that way you know its fully metabolized and your serotonin is up.

 

5htp+dxm = serotonin syndrome.

"It has been a matter of debate as to whether 5-HTP in combination with MDMA or LSD can cause serotonin syndrome. Personally, having experienced seizures after using 300 milligrams of 5-HTP on the comedown of an LSD experience (12 hours post ingestion), and having seen a friend manifest a precisely similar reaction after taking 300 milligrams subsequent to MDMA, I will have to say that I think that 5-HTP and L-tryptophan should not be mixed with any serotenergic drugs."

 

I would like to fill you in on the dangers of 5-HTP... The other day SWIM had picked up some dex and some 5-htp not thinking at all about adverse reactions because of how weak SWIM thought 5-htp is.... SWIM had also taken 5-htp the day before a DXM trip before and noticed a more clear mind/ no rigid muscle movement and a lot more control over speech and actions but was still tripping mentally and visually so and music sounded amazing!!

SWIM thought that this would be the same. So SWIM took 2 5-htp capsules early that day (roughly 11:30 ish AM), went to work and thought nothing of it. SWIM got home at 5 PM knowing that SWIM's brother was gone for the weekend SWIM took 7.5 ounces of DXM polistirex filled syrup(delsym). SWIM took two more 5 htp capsules just to give it all he had. Within an hour and a half SWIM became very warm and started tripping way too hard. The following symptoms came in waves except the visuals and auditory hals they were constant: very strong Open Eyed Visual's and Closed Eye Visual's, delirious thoughts, extreme auditory hallucinations (repeating sounds, Lazer noises, music that he was previously listening to etc), explosive diarrhea, high fever, extremely fast heart rate (couldn't find heart monitor or thermometer so no exact fact on those) SWIM is extremely lucky he is a very experienced, over 5 dozen times on many different things, "tripper" if you will. SWIM knew that the fever and heart rate were the problem so luckily it was about 5 degrees F outside so swim knew to go outside to cool off.

Also, SWIM has read a lot about DXM and knows that there are some reports that Nicotine almost stops all DXM activity... So SWIM went outside and smoked a cigarette all symptoms slowed and became tolerable if not pleasant.. The cold was amazing and made the heart rate slow and the fever fade, the spinning needles in the skin feeling faded... nicotine helped a lot.... and the cold helped too. So SWIM went through this process for about 8 hours up and down having hot flashes and melt downs so bad that SWIM thought he was dying so many times that he just gave up caring... all this until he could fall asleep. It is a lot worse than it even sounds... I literally was like schizophrenic for part of the trip hearing voices and people talking to me in my head...

SWIM was pretty much tripping still for the next 3 days. SWIM does not advise this to anyone although SWIM had an amazing spiritual experience with God, himself and it was probably the most beautiful psychedelic experience of SWIMS life... SWIM probably could have died and should have gone to the ER but luckily mentally and physically knew what to do

SOOO dont try to do this.... ever ever ever... SWIM was lucky... and still probably fucked up SWIMS liver, heart, and brain chemistry for a month or two... so if you do try it which you shouldnt..... try 5 htp the day before and dont exceed one bottle of dex cuz this shit like doubles the potency of dex....

 

Cherokee I appreciate that you have a curious spirit but you are always asking whether it's ok to mix dangerous drug A with dangerous drug B. Maybe you should cool down on that front man. Just enjoy each drug on it's own, not worth not waking up.

 

i mixed 5htp and dxm more than once, and never had any noticiable adverse affects that couldnt be attributed to dxm alone. all the stuff round rhombus described can be effects of dxm alone. i never got serotonin syndrome from it either, but i remember reading that the way they are metabolized and broken down in your body causes the 5htp to be neuro toxic or something. i just dont remember the specifics, so after i found that out i stopped trying to boost the dxm with it.

 

Cool I did not know that. Thats nice to know.. I am glad that it was just the DXM than... because that was terrible... now that I think about it maybe it was just because I did it to frequently and didn't let the DXM polistrex get out of my system long enough and just dosed on top of a dose....

 

oh man, thats why i love the polistirex form. theres plateaus that i can only get to with (mainly) polistirex, sometimes to speed things up i put a little bit of hydrobromide on top. when you get that polistirex floating around in your system for a few days, crazy shit happens. stacking doses of polistirex on each other, i worked that shit out to a science.

man, thats the type of shit i aim for when doing dxm. the laser noises, feeling like an alien took over my brain, i love it. and i love being in the cold on it too. i was hearing music in my head one time that i cant even describe. i love the noises. when i ride the buses sometimes it brings back memories cause of the oscilating sounds the bus makes. buses and big air conditioning system type things.

 

5htp is usually taken because it is a precursor to serotonin the stuff that makes ecstasy work. Also if you take an maoi and then dxm you're going to trip for like 3 days

 

Yeah dude it takes time to like look back and be like "ohhhhh thats why that happened.... but yeah the stacking doses is most def what I probably did

 

I disagree if you take an maoi then dxm ur gonna wish you where dead. I accidently mixed an maoi when i dosed on dxm and it was one of the worst experiances of my life. Not only did i not trip at all it def. didn't last 3 days

 

I guess the only thing we can take from all of this is the usual rule.... THINGS EFFECT US ALL DIFFERENTLY THAN THE NEXT GUY.... just because we all can relate on some things in tripping is cool, but on a medical level we have no idea what is going on inside of us while we are tripping compared to others... so be safe do a shit ton of research and always ask questions, questions are good.....

 

well, medically, i do know, for the most part, what everything i put into my body is doing. if i didnt, why would i be so ignorant to ingest it? when you know how the drug lives and dies inside of you is when you can understand how to really use it to its full potential.

 

neurochemistry of hallucinogens is soooo not understood by scientist... they may know the chemical actions that happen but they have no idea how or why it does what it does and or how it effects the brain because not that many people donate there brain to science and record the amount of drugs they have done... so there is not physical evidence other than in mice... and animals... I didnt mean physically... you'd have to be an idiot not to find out what it does to your liver and stuff like that...