You'll probably need at least 40mg. I'd go closer to 60, and since you said you didn't notice it that much, you're probably going to have to dose that high to get good effects.
damn, thats so much powder. i brought like 30mg on a trip cus i knew i wasnt gonna be able to smoke but now i proly will just save it to be smoked (which is also hard for me, wtf, either that or its reall weak and doesnt get me high. idk. i guess 018 is the one to try next
I think 073 is just really weak, at least for me anyways. I ate 60mg about 6.5 hours ago on an empty stomach and I didn't feel shit. When I smoke it, I have to smoke around 20mg to feel the affects. I may try 018 next but my interest in the synthetic cannabinoids is pretty much gone.
You should try CP 55,940; that's 45 times more potent than THC and active at .25-1 mg. I haven't tried it but I'd like to and that is what I'd be interested in if I were to try a synthetic cannabinoid.
yeah, i had to smoke a lot of 073 to feel it. like 25mg or so, then i was nicely high for about an hourish
Shit. 15mg gets me baked for like 2-3 hours. I don't know what your guy's problem is, to much of a down regulation of cannabinoid receptors? I would guess so.
I don't think cannabis use causes downregulation of receptors since they are made for it and not forced open like the dopamine/serotonin is in ecstacy and methamphetamine. I think if anything, it's temporary, I do know that the brain shuts off cannabinoid receptors after a certain limit is reached, so being daily saturated in THC can make them temporarily closed, but I think that's a lot different than if they had been downregulated, which seems more permanent.
Down regulation happens with almost all receptors. All it takes is (to much) activation of the site in order for it to down regulate itself. Down regulation is only temporary too. There is nothing bad about that. Love you man <3
what about dosage for oral jwh-018 and duration? I'd like to lower my chances of cancer, if possible.