Yes this is a copy/paste, yes I know it's dangerous, the materials are hard to get your hands on, and that it's a very finicky process. Yes, I LOVE me some acid. Materials: 1. Ergotamine tartrate 2. Hydrazine hydrate 3. Hydrazide 4. Hydrochloric Acid 5. Sodium Nitrite 6. Sodium Bicarbonate 7. Diethylamine 8. Ether 9. Flasks 10. Filter paper 11. Heating mantle 12. 2 liter three-necked round bottom flask Time: Approximately 36 hours. Process: STEP 1: In a 2 liter three-necked round bottom flask add to 2 grams of ergotamine tartrate about 1/2 gram of hydrazine hydrate. Exercise caution when adding the hydrazine hydrate because it is very poisonous, particularly to the eyes. STEP 2: Place a condensing column on one neck of the flask. Place a stirring device in the center neck and place a separatory funnel in the thick neck. (Note: hydrazide hydrate may be added through a separatory funnel although it is not necessary.) STEP 3: Place the flask on a heating mantle and simmer the solution for 2-3 hours while stirring occasionally. STEP 4: Remove condensing column from flask and continue to cook for 10-15 minutes or until the original solution is reduced by half. STEP 5: After solution has cooled, pour the solution through filter paper and collect the crystals that formed. Wash the crystals in a small amount of absolute alcohol. STEP 6: Dissolve the crystals in about 30cc of diluted hydrochloric acid. (Note: diluted hydrochloric acid is mixed at a rate of 1 part acid to 10 or 15 parts water.) STEP 7: To the hydrochloric acid solution add about 15cc of a solution of sodium nitrite diluted in water. (Note: one part sodium nitrite to 10 or 15 parts water.) Let this solution stand for about 30 minutes. STEP 8: To this solution add about one teaspoonful of sodium bicarbonate (baking soda) to make the solution basic. STEP 9: Place this solution in a separatory funnel and add to it an equal quantity of ether. Shake this solution gently for about 5 minutes. STEP 10: Separate the ether solution from the separatory funnel and keep the ether solution. The remainder may be discarded. STEP 11: Cool the ether solution to 0 degrees Celsius and to the solution add a solution of about .5 gram of diethylamine mixed with ether. STEP 12: Maintain the solution at 0 degrees Celsius for 24 hours, stirring it occasionally (perhaps 4 hour intervals.) STEP 13: Remove the solution from the ice bath and allow it to stand at room temperature for about 2 hours, or until it evaporates. The remaining crystals will be crude LSD.
Not familiar with that method, but yes, it probably is real. Good luck finding ergotamine tartate and diethylamine.
Ummmmm, not that I know anything about such things, but wow, no precautions, nothing. I am no chemist or synthesist but even I have read that to control hydrazine such that it does not EXPLODE you need a dedicated Nitrogen environment. That's just one issue . . . .
Hydrazine is also very poisonous, no mention of a fume hood... This sort of strikes me as a cliff notes version of a real recipe. And no one who needs to ask here if a recipe is real has any business trying to make LSD. It's 2 years of college chemistry at the very least before attempting.
I actually realized, this morning, that I have easy access to all of those needed ingredients. I have some in my house, but I'd need to buy some DEET and NaOH (for the diethylamine) if I ever wanted to proceed with things. And out of curiosity to you all, I never have taken LSD.
for step 1: that's why we have safety goggles and lab safety protocols... for steps 3 & 4: you might want to put the flask on a double boiler instead of a heating mantle just to make extra sure it doesn't explode for step 8: add the baking soda slowly. you don't want a solution of hydrolyzed ergot alkaloid, hydrochloric acid, and sodium nitrite burning your face (oh the joys of safety goggles) if you want, you can further purify by taking your crude product, making it acidic again by adding it to some HCl solution, mix in more ether, basify, separate the ether phase, evaporate the ether, repeat as desired. also, if you really want to maximize productive output, get yourself a chromatography column and a UV light. In an alkaline solution, d-lsd and iso-lsd freely interchange with one another in solution, so after the solution hits equilibrium, make it acidic, separate the d-lsd visually using the column, rebasify the iso-lsd phase, repeat as desired. try to minimize UV exposure to the d-lsd, though, as UV light will make it decompose at either of it's stereocenters. (... I remember more about chemistry when it's 3 in the morning lol.) *edit* whoops! putting your rough LSD into HCl would destroy it, as the chorline will bind to the C5 stereocenter and destroy the bond with the diethylamine. try H2SO4 instead when refining
Thanks dude (andallthatstocome). I'm not 100% serious about this at the moment, I'm just archiving various methods and comments to mull over for some time, then worrying about where to get the materials from. I'm going for a doctorate in biological enegineering after I go for two years to be a biochemical lab. tech., so it is a realistic thing for me in the future, I'm just doing some preliminaries in my free time to get the ball rollin.
