So my girlfriend is really interested in trying some of the 2c-e i have. But she has Crohn's disease which is "is an inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from mouth to anus, causing a wide variety of symptoms. It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is at its worst), vomiting, or weight loss" I was always weary of her trying new drugs other then weed. But about 3 months ago she tried shrooms 1/8th and had a bad trip and didnt like it but was still fine and healthy, so she got interested in LSD and reasearched a bit and found out it wont hurt her so i let her try that and she did fine. but 2c-e, im not to sure about. I mean it corrodes your nose it feels like. and makes you puke 80% of the time. anyone have any who has tried this or has chrons that could help me out? Thanks- Kid
To my knowledge no one has ever died from 2ce, I don't have Chron's disease but I'm sure she'll be alright. I would be more worried about frequently using various psychedelics for something like that rather than any single psychedelic in particular. Also Nasal administration completely bypasses your GI tract, I think. Where did you hear it makes you puke 80% of the time? I've never puked from it.
my advice would be to have her try a low dose first to see how her stomach handles it. then go from there. or if you are able to maybe just do lsd again- pretty tummy friendly.
Psychoactive substances are often insufflated nasally for the purpose of intranasal absorption through the mucous membrane, which is often more rapid, or more complete, than gastrointestinal absorption. For a substance to be effective when insufflated, it must be water soluble so it can be absorbed into the mucous membranes. This practice is commonly referred to as snorting, bumping, railing, or doozing.[4] Although the majority of a dose of insufflated drug is taken up through the mucous membranes, some enters other parts of the gastrointestinal tract where it may also be absorbed. This is because some of the dose drips down the throat and into the stomach. This effect is commonly referred to as the 'drip' and is often unpleasant to taste. -wiki info So you would be getting a severely diminished absortion from the GI track (which is good) from insuffalation. But 2ce was foul when I snorted it.
Snorting it hurt like the devil. A good reward however. But still. I was in complete pain. After twenty five minutes it was bliss.
If you choose insufflation just be sure to go slow using exceedingly small bumps, spaced out and between both nostrils otherwise vomiting is a pretty likely outcome. And unpleasant is an understatement! That said, insufflating it can shoot your mind off with some amazing force. On the gastro side of things, I've always know 2c-e to produce bad gas. It's a reasonably small inconvenience usually but I'm not sure how it would effect a person with Crohn's. Might be best for your gf to dose small at first and work her way up over time gauging her own reactions to it as she goes. It could be over any number of experiences or even one if time isn't an issue.
If she can get LSD then get her to do that over 2C-E anyday. Every 2C substance except T-7 has cause me stomach pains and sickness. Never thrown up but i never throw up off any drugs except a couple of times on excessive amounts of Alcohol (and once off a high dose of Subutex which i took unknowingly when i was really young)
Lol everytime i snort 2c-e i snort it till i puke, thats how ik i have a good trip. when i eat it i puke alot too lol. she will prob snort it. shes taken about 11 hits of acid at once so i think she can handle it. ill probably just warn her of the extreme burn and let her snort it. shes dosing friday so ill update and let everyone know how it goes.
2ce gives me the feeling of having bad gas or the need to make a movement when there is nothing there. I don't know if that means anything or not but I'd be careful or even advise against it. Chrones is serious business.
I know about Crohn's from a personal friend with it, and were this friend even interested in "this line of work", I'd seriously advise against it. I agree, that with regard to how the GI system is going to react should be a bigger concern across the board of sikes rather than fixated on just one relatively safe one that I too have never puked from, am on now, and not even a tinge of nausea has hit me in any subsequent time aside from the first 2c-x experience. That said, I would acuallly tread with caution with anything that could upset his/her delicate GI system's chemistry especially with something as serious as Crohn's, please, read the liturature before going ahead with the 2c-e (or really, any sike since virtually all but acid can and have proven to cause upset stomach, even MDMA can occasionally under the wrong circumstances). Crohn's is a really painful, and quite permanent, quite disablling disease that it only seems normal that a simple little dose of shrooms would set on puking given what i know. it can be treated though with a mix of belladonna and phenobarbital, but that, Donnatal, is addictive as they come, and it's weird, it's like becoming addicted to jimsonweed, but at the time also becoming a barbiturate addict complicitely just since it's such an effective medicine at masking and controlling violent fits and shit within your GI tract. Needless to say, there are other drugs, I only know all of this because it's the drug I chose to combat a similar though less serious GI problem I have, gastritis (plus IBS & GERD, which is strange I'd even be giving this advice at all since I never get sick no matter the sike, not even last night's cactus trip sent me puking. I'm just a tough ol' goat. But Crohn's is much, much worse, and fucking with its delicacy is asking for months of starvation, vomiting, maybe even tube feeding (and I doubt your friend wants that). Last of all, everyone who regulars this joint knows my crazy stance on sikes, and so for me to be saying this (while coming down from some) should count for something; I'm trying to help you avoid catastrophe. Please heed my advice, disregard anything anyone has said unless they too have witnessed the tragedy that Crohn's can cause (like a relative of mine's recent removal of his entire large intestine to aid in inflammation control, and only to what extent that sort of major life-changing/diet-changing surgery will allow, as in my relative's case). Crohn's can kill, remember that, it's true, though unlikely, it is a possibility if proper healthcare steps are not followed, and IMO 2c-e doesn't fit within that dietary regimen, no matter the fun someone with Crohn's may have until they start complaining about sharp pains..... From there, it's history, and you already knew this or wouldn't be asking for advice. But for what it's worth, I'm being honest and have a close friend and a relative that both suffer from this. There are theories abroad too, but supposedly an organic vegan lifestyle can help with the painful cramps and such, I have heard there's a tie to red meat and Crohn's (probably having to do with the fucking hormone therapy on cows). Good luck and stay safe and keep your friends safer! Hey, maybe this::beatdeadhorse5:is the case, but this is the intention here: eace:
this is ever so true, start low like said, and work your way up in successions until you reach your desired effect. the quickness with which snorting 2c-e (or any 2c-x) hits is remarkable this way and is also exponentially more powerful this way, as with recal admin. In fact, it roughly equivolates to the doubling of a dose orally when snorted. So snorting 15mg is like eating 30mg and having it hit and plateau within ten min. Maybe because of my GERD, IBS, or gastritis, but I've always had this effect the day after 2c-e too. Especially when methylone was involved. Otherwise, I don't get even a twinge of illness.
I've snorted enough 2c-x's to say that this one burns probably like no other, but GB is correct, the taste is absolutely foul, but the comment just below here about 25 min. in and complete bliss, in my experience, the burn goes away within 15 min. & that's when the bliss hits too. I have since traded in my snorting of PEA shoes for encapsulating them and simply eating them because I worry that after all these years I've finally deviated my septum. I dunno if I have or not, I guess if I put a shoestring up there and was able to pull it through the other nostril I'd have an answer. I don't want one though! I still love my coca.
My last comment on this topic for now, but this was my original thought (especially if she can handle a tenstrip plus one hit, that's a lot of lsd, I can't say I even have ever gone that high (though argueably I've had comparable amounts due to how much was assumed on the blotter, the fourway windowpane, or my personal favorite, the gel tabs of acid that melt on the tongue. Six of those had me scratching the ceiling for about two days. And best of all within this given scenerio, I had no belly aches, I did have a rather sore back, but that's it. I'd take lsd any day head over heels without even thinking of snorting any 2c-x until or up to the point that I could no longer get lsd, and depending upon how many quality lsd trips I had, I may not even desire to venture further for fear of ruining a great spree of wonderful experiences.
Yeah I know several people who have puked after railing 2c-e, I never once did though. And I have snorted 30 mg at once up one nostril before. I guess it depends on how strong your stomach is.
2ce has really fucked with my stomach before and may have been the cause of my friends stomach related issues (she mysteriously had a bunch after ingesting 2c-e), I'd probably just not have her toys with the RC's, best of luck
do you know any details? i feel like it's more intestinal/GI problems, for me. not serious, but annoying and worrisome. trapped gas, and feeling like i have to shit, or it's hard to shit
once you are done researching, and if she decides she wants to try it afterall, can i suggest that before she snorts it, she treats her gut for a few days beforehand with slippery elm gruel, eating a small bowlful before the snort... slippery elm coats and soothes the GI and may help lessen any neg effects from the drip...
She had a lot of problems with keeping meals down afterward, generalised stomach pains, lots of diarrhoea. She actually ended up getting diagnosed with something related to those issues, though it has been a while since I have last associated with her so I couldn't exactly pull out the name of the diagnosis. But yeah it seems like the stuff can be pretty rough on the stomach, I was able to handle it quite well for a while but towards the end of my trials the shit just had me clenching my stomach the whole time, unable to really enjoy the experience. I was dosing with the stuff fairly regularly (so my fault really) and she did it about 3 times in a week and then some, we got a bit carried away for something we knew was an RC. Would you care to share how close your dosing intervals were, how many times you've taken it and dose measurements?
