Antipsychotics interrupt a trip, while Benzo's lower the anxiety - any truth to that?

I guess the title says it all. I have zyprexa and clonazepam from a long time ago, (big surprise, turns out I didnt need drugs).

I read somewhere that they can be life saving in a trip gone wrong. I hear the order in which one should do things if a trip goes wrong is the following:

1. Try to take nothing. Badtrips can be very educational, and the bad feelings usually subside.

2. If that fails, clonazepam will not make you trip less, but will tame the anxiety associated with it.

3. If all else fails, a Antipsychotic will abort the trip.

Anyone know anything about this? Your help will be appreciated!

 

Took a little .50 klonopin when taking 2doses.. just took the edge off the trip. made it really a social trip, could play my guitar and not get lost like I sometimes do... did not cancel it out.. just made it smooth..

wouldnt fuck with anti-psychotics.

 

mixing benzos with psychedelics can be LIFE THREATENING. Along with being a pussy move. As far as I'm concerned there is no option two or three. You've got option one, good luck

benzos can actually abort the trip as well, just like anti-psychotics. Neither is recommended, you are putting yourself in more danger doing this, just get through the experience and learn why it went to shit.

 

Would you kindly elaborate on what the dangers are? (I'm not testing, I'm just asking, I know youve got lots of knowledge on this. Respect!)

p.s. lol @ along with being a pussy move. I don't know if you know this but sometimes anxiety can get pretty crippling for some of us. Not everyone is capable of eating a strip and a half accidently and keeping it together

 

Antipsychotics of the 2nd Generation, aka Atypicals, are 5-HT2A/2C receptor antagonists. Strong ones. Psychedelics work as agonists (opposite of antagonist) at those sites. So, yes, you cancel the trip with an Atypical Antipsychotic.

Benzos act as GABA receptor agonists, a completely different mechanism. They work to turn down the "volume" knob on your brain. Thus they will help quell any sort of super-manic or bizzare problems with psychedelics (the 5-HT2A/2C agonists) without removing their core quality!

 

So in short that's a yes! You seem to be really informed when it comes to those things - thanks for sharing your knowledge! I will do my best not to take anything when I trip, but I'll be sure to keep em' handy.

Thank you!

 

I know a good deal on the pharmacology of common psychoactive drugs. I don't have much first-hand experience with most of the drugs, but have heavily researched a good deal of them.

 

haha that actually sounds kinda like me. I'm scared to try psychedelics but i'm extremely fascinated by them.

 

I don't think you know what you are talking about. These are substances that the hospital will give you when you start freaking out during a trip. They are not life threatening if used properly. I would not trip without them, and have used them many times to abort and ease bad trips.

 

And do you use mostly benzo's or Antipsychotics?

 

I think Mr Writer Is saying the "End of Life" referring to LSD as a living organism .. taking the anti psychotics, will "end the life" of the trip... Not the person..
when I worked in a hospital. I rarely seen people come in hallucinating on true psychedelics. Mostly cocaine psychosis / They may give them benzos @ intake, but follow up with anti psychotics a day or 2 later..

 

You are correct. The type of psychosis that is medically recognized is NOT the type people talk about with regard to visual hallucinations and shifts of perceptions in psychedelics. The type medically recognized is the type that responds to antipsychotics, which are Dopamine Receptor Antagonists. The modern medical hypothesis is that psychosis, be it Cocaine (a Dopamine Transpot Agonist), or schizophrenia (caused in part by an overactive Dopamine Type Two Receptor activation), is caused by over-excitement with Dopamine. The catch is that psychedelics do not activate Dopamine, but rather, like I stated above, activate the various Serotonin (5-HT) receptors.

Essentially they are two different ball-games.

 

I wonder why psychedelics can trigger a psychotic break then...

 

A true psychosis is rare, but it is still not completely understood. Ideas tend to do with the potentiation of another neurotransmitter, Glutamate, which is related to agonization of 5-HT receptors and in schizophrenia. Remember, I said Dopamine is part of the explanation of schizophrenia, but not the whole story. Most psychiatrists, including my own, believe Glutamate has a role as well.

 

A regular on here "CannbisSoul" took DPT with some friends. One of them decided it was too intense, and took a few benzos. Their breathing stopped and their face turned blue. I believe CPR was needed to keep their friend alive. This is the only instance of such an interaction I am aware of, but given his friend is ok with benzos, and ok with psychedelics, and began dying when he combined them, I'm very wary of mixing them. But you are right, hospitals do give you benzos if you are tripping out.

Haha I know anxiety well, I have pretty bad social anxiety and was medicated for years with SSRIs and a few benzos. But I gotta tell you, on 15 hits, there's no room for anxiety i think i could have been arrested and i would have just smiled at the cop and told him everything will be ok, because the beauty is in everything :love: :2thumbsup:

 

Ahhhhh thats awesome. I'll find out sooner or later.

About the benzos, maybe he took too way much benzos because respiratory failure is a sign of benzo overdose. I'd be curious to know more about this story, because as others have said, Benzos are often the saviour in this case. On the other hand benzo OD's take a few hours and last for 12 to 36 hours, so maybe it's not the benzos.

I did read another story on erowid where someone was on some phenethylamine and his lips turned blue and he stopped breathing. I know it's not a tryptamine, but still...

 

I've tripped on benzos more times than I can count and there is no dangerous interaction at all from my experience, they tend to end the trip themselves.

 

Very good to know good sir, I'll be sure to have em' handy when I trip.

 

IDK, i agree with Writer, not that this is an argument just an educated discussion...I have had a few bad trips in my experiences with various psychedelics, and i have had benzos on hand at the time. However i have never taken benzos when i have been having a bad trip. I personally feel as though sometimes, a bad trip can actually show you somethings about yourself and your environment, an you can LEARN from the experience.

 

It's never occurred to me to do anything other than the trip in its entirety. But if I did want to I'd pay attention to magical mystery.