does anyone know the equivalence of roxicodone to actiq

Discussion in 'Opiates' started by ripped103, Dec 22, 2011.

  1. ripped103

    ripped103 Member

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    i take 16 30mg roxis a day
    this would be done through my pain management doctor.but before trading in my 480 roxis a day, i would like to know the dosage of actiq i would get
     
  2. etkearne

    etkearne Resident Pharmacologist

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    Actiq would just be for breakthrough pain. The doctor would prescribe something else like a Fentanyl Transdermal Patch for around the clock pain relief. Does your doctor really just give you 16 x 30mg Oxycodone per day? Why do they not give you like 3 x 80mg OxyContin with "Roxycodone" for breakthrough?

    If you are just trying to pretend that you are actually getting this from a doctor, there is no need to lie. We don't care really. If that is the case, if you are taking 16 x 30 Oxycodone IR per day, you would probably want to start with around 1000 micrograms of Actiq three times per day if you are taking, say, 90 mg of Oxycodone at once each time you dose. That number comes from my opioid conversion app so it is not out of thin air.

    BUT, I would start much lower, like 400 micrograms, in case you don't have a complete cross-tolerance. You don't want to die. Fentanyl is incredibly strong.
     
  3. ripped103

    ripped103 Member

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    no im on 400mcg of fentanyl patches every other day plus the 16 30s of roxis a day plus 2400mg of neurontin a day and 30mg of flexerral a day.i was on 24 30mg roxis a day 120mg around the clock but my doc left and the new doc lowered my dose to 16, 30s a day with the other meds.
    since im still in extreme pain she mentioned actiq instead of the roxis but im not sure this will work.i was trying too see the equivalent of the oxys i have left to the actiq lollipops before i tell her anything.
    i have been on pain meds fro 10 years thats why the large doses and i will be on them for the rest of my life
     
  4. etkearne

    etkearne Resident Pharmacologist

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    Yeah. The equivalence ratio is that 30 mg Oxycodone IR = 450 micrograms Fentanyl IR (Actiq). So you can figure out what you need from that I hope. Let me know if you need more information. Good luck and work towards being pain free!
     
  5. ripped103

    ripped103 Member

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    where is the chart where you found the equivalence for roxicodone to actiq(fentanyl citrate.
     
  6. etkearne

    etkearne Resident Pharmacologist

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    Ripped- it is on an IPAD app that I have which is designed for doctors. I will post the conversions below (found in the app) which are not pulled out of my ass- they are used by medical professionals daily with this app:

    10 mg Morphine IV

    = 30 mg Morphine Oral
    = 1 mg Alfentanil Subcutaneous
    = 0.3 mg Buprenorphine IV
    = 1.2 mg Buprenorphine Sublingual
    = 165-180 mg Codeine Oral
    = 10 mg Heroin (diamorphine) Subcutaneous
    = 0.1 mg Fentanyl IV
    = 0.3-0.429 mg Fentanyl Transdermal/Buccal/Sublingual
    = 26-30 mg Hydrocodone Oral
    = 6-8 mg Hydromorphone Oral
    = 1.5 mg Hydromorphone IV
    = 1-4 mg Levorphanol Oral
    = 300 mg Meperidine Oral (Demerol)
    = 75 mg Meperidine IV
    = 2-10 mg Methadone Oral (DOSED VERY DIFFERENTLY!! SEE NOTE)
    = 15-20 mg Oxycodone Oral
    = 12 mg Oxymorphone Oral
    = 180-360 mg Propoxyphene Oral (Darvon)


    NOTA BENE: Methadone does not follow a linear dosing curve. Why? It is an NMDA antagonist in addition to an opioid agonist. NMDA antagonists lower opioid tolerance in both the short and long term. Thus, to equate Methadone to oral morphine, one must consider the dose of the morphine. If we are talking less than 100 mg of Morphine, then the equivalence to Methadone follows a certain pre-set conversion (10 mg Methadone). BUT, from 100-500 mg of Morphine, the conversion allows the Methadone potentiated so that instead of being 10 times as powerful as Morphine, it becomes 20-30 times as powerful as Morphine. And from 500-1000 mg of Morphine, Methadone is up to 50 times as powerful per milligram!! That is why it is so perfect for both long-term pain relief AND addiction maintenance.
     
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