Good mixes, bad mixes

Hello!

I'm curious about which substances you combined together and what kind of trip occured after. Which ones would you recommend? Which ones would you warm people to stay away from?

I got a few fantastic trips combining different substances, to enhance their good initial sides or soften their less desirable effects. Some trips, on the other hand, turned out to be a lot more difficult than I expected.

Good/interesting mixes

-LSD + MDMA. Gotta love the classic candy flip.
-HBWR + MDMA. Very interesting and deep though it's a bit tough on the stomach at first.
-Mescaline + MDMA. Wonderful visuals and feeling of oneness.
-HBWR + kratom. Sensual pleasure out of this world.
-Peruvian torch + MDMA + a tad of ketamine. Dreamy.
-MDMA + ketamine. So spaced-out yet so lucid at the same time.
-MDMA + half a speed + LSD + a tad of ketamine. This combinaison is orgasmic, no joke.
-Mushrooms + MDMA. Sweet and lovely.
-2C-E + MDMA. Positive and very, very trippy.
-BZP + LSD. Very pleasant body feeling and great mood, visuals and feelings of being connected to everything around me.
-BZP + MDMA + a bit of ketamine (that's more than a tad in my book). The body high and empathic feeling were out of this world, incredibly intense energy and joyful mood.

Bad/uncomfortable mixes

-Speed + 2C-B, both at high doses. Mentally it was great, but physically I felt like I was a fuse about to blow up! This combinaison must be great at lower dosage though.
-LSD + ketamine. The OOBE's (out-of-body experiences) I got from this mix were pretty disturbing.
-Salvia + a high dose of MDMA. Too spaced-out, REALLY too much.

What about you guys?

 

marijuana + mdma

 

Double post sorry!

EDIT: I didn't took weed in consideration because I think it goes with everything.

 

ive never combined any psychedelics
the only psychedelics ive done are mdma/ecstasy and ketamine

 

^^^me neither. but i've tried a few (mushrooms, LSD, 2ce, 2cb, salvia, ketamine once, mdma once, 4-aco-dmt once....mescaline once, kinda)

 

~100mg MDMA + *7*mg 2C-B = A truly unforgettably magical roll, full of insane visuals and a thundering body high. The euphoria was over 9,000.

1/3 hit of shiva + repeated ketamine insufflation of ~50-100mg lines for someone with no ket tolerance = ridiculously complex visuals and a sense of rushing through spacetime at the speed of light. hypergalactic.

175mg MDMA + unknown small dose mushrooms = very euphoric and beautiful time, mushroom harmonization with universe plus molly harmonization of emotions

50mg 2C-B + 250mg Ketamine insufflated at t+1hr = A grab-you-by-the-balls ++++

120mg MDMA + 250mg Ketamine insufflated at t+1hr = An insanely heavenly K hole that was filled with a radiant euphoria bursting from everywhere in wild abandon. Blissed out infinitely, a top pick for sheer recreational value.

35mg aMT + 50mg DMT vaped at t+4hrs = tryptamine bliss upon tryptamine bliss, prepare to meltttttttt

And tons of combinations of things with cannabis or even some JWHs. The most notable would be

50mg MXE + cannabis bowl at t+30mins = An impossibly bizarre and rich tripscape filled with these dissociative-esque stark-contrast hallucinations and "interpretations of the world" (weird dissociative shit if youve never done it) along with a powerful loss of short-term memory and basically paralysis of most kinds of movements through sheer spacetimefuckery; brain thinks "if you move foot forward it will be on alpha centauri", and along with that your leg is numbed out from the anaesthetic properties.

Also combined Syrian rue with cannabis with great success. prepare to get highly stoned.

 

Did you take the syrian rue along with some MAOI? I'm curious if it's as effective without the inhibitors.

 

I don't really know all the combinations I've taken.
Don't think I've really ever had much of a bad one either...maybe too much booze and some opiates...lorazepam i think it was.
The best ones that are actually worth remembering and doing again for me are:
Ketamine + MDMA/MDA - Pretty much the best drug combo out there imo (weed is a given as being included in these combos). A low dose of an opiate could make this combo even better...
LSD + Ketamine - Such an incredible trip. Can be extremely weird. I don't know why you don't like this combo OP...I've had crazier out of body experiences on high doses of K by itself. Watching the sunrise on this combo is incredible .

I guess really MDMA/MDA/etc. goes well with just about anything that isn't already too speedy to add another stim to.

 

a couple of months ago a lot of interesting mixes can be found on Buzz-wholesale

 

Syrian Rue is an MAOi, that's why I took it to potentiate weed

 

2hits LSD + 30 mg 2C-I - perfect synergy, extremely trippy alien like visuals, extremely lucid
2hits LSD + .5 g Mdma - Loads of energy, very blissful, grand appreciation for music
Half 1/8th Mushrooms + .3 g Mdma - Euphoric, went back and forth from lethargy to hyperness
3hits LSD + 1/8th Mushrooms - one of the most powerful over the top trips to date, ++++, out of this world visions, time completely ganstunkfutz, nirvana, alien connection, god connection
1Cup Mescaline Juice + 1Hit Lsd + 1g Mushrooms - a muddy mess of dreamy bliss
2Cups Mescaline + 50mg Dmt - a gentle dissolve into hyperspace, a few insights, and a extreme visual pool on the returning phase
1.5g Mushrooms + 30mg Oxycontin - took the oxycontin at the very very end of the trip, nice blissful way to end the night and nod off, with nice gentle visual stimuli
50mg 2C-B + .2gMdma + KobeBryant SuperpurpandyellowWEed - Bright lucid visuals, amazing body high, almost a liquid flow to it, kobe increasing its effects

 

Good Mixes:

1. [Dextro]amphetamine + Opioids (my favorite high of them all)
2. Methylphenidate + Alcohol (not that great, but better than the sum of the two separate)
3. Cannabis + Benzodiazepines (takes the edge off the 'creepiness' of pot)
4. 2C-I + Opioids (adds to the empathogenic effects)
5. Cannabis + Caffeine (one of my ol' favorites before I discovered real stimulants)

Bad Mixes:

1. Amphetamine + Caffeine (nervous wreck)
2. Zyprexa + Cannabis (you turn into the living dead- zombie)
3. Opioids + Barbiturates (well...haha...no explanation really needed there, huh!)
4. Yohimbe + Amphetamines (a trip to the hospital in the makings!)
5. Alcohol + Benzodiazepines (Xanax and Alcohol in particular almost sent me to jail once)

That is my contribution.

 

I often heard by some people around me who tried that mix that it was like a mental thunderstorm, hence why I didn't dare to try it. Glad to hear it went good for you.

Dammit!! Living on the edge eh?

 

^There are moments of chaos where the acid and mushrooms sort of lose there synergy.

I remember my friend who was on the same dose as me kurplunk down on to the bed whilst he exclaimed "oh dear lord Jesus Christ save me", very whole heartily as if he was deathly terrified and he really needed the grace of the lord.

But it comes and goes, once you reach the stable point it is very beautiful, very powerful, deep trip.

 

I will try any drug or drug mix once provided the following:

1. The doses are well researched and there is no question in the doses I am taking.

2. The route of administration is likely not going to negatively impact my health. That is, no IVing since I have NO access to 100 percent safe needles.

3. Never try a combination that has not been tried before with safe results. So, staying with the barbs plus opioids theme, I would not try doses that were anything more than "very low" to begin with. Take less than the sum of the two separate entities.

 

Weed doesn't effect any Monoamine Neurotransmitters (Serotonin, Norepinephrine, Dopamine, Histamine, Melatonin. It only indirectly potentiates dopamine in the Nucleus Accumbens, but an MAOI wouldn't effect this.

 

Hah, this whole time I thought Delta-9-THC was broken down by MAO. I guess I was just feeling the effects of syrian rue + weed rather than a direct potentiation of weed.

 

Shrooms and a good dose of caffiene = :feelscrankyman:

Found out during a wake n bake where I drank my usual half pot of coffee.

 

An interesting mix I did yesterday was methylone and a low dose of mushrooms, but it's far from being a comfortable combinaison. In fact, it was quite the mental tear-up and it's the first time ever I got scared shitless during a trip, to the point of not being able to calm me down.

But I guess that being with a large group of people, all high on methylone too, and listening to some hardtek during the whole experience didn't help much.

 

THC functions as an agonist of a G-Coupled Protein receptor (the CB1 and CB2 receptors). Thus, it mimics the effects of a neuropeptide, anandamine. Thus, it is not a Monoamine and will not be affected by an agent that effects such transmitters.

It is a good question to bring up, though, as it wasn't until about 10 years ago that people actually figured that out. It was anyone's guess as to how Cannabis worked until then.

Being a G-Coupled receptor agonist, THC works through secondary mechanisms which tune the volumes of a various number of neurotransmitters (some ARE Monoamines) in very specific areas of the brain. Mainly, it works to decrease GABA transmission in the midbrain, which leads to retrograde signal transmission and produces the classic "de-realization" and sense of novelty that comes with Cannabis.