My pain management clinic is involved in drug studies with numerous pharmaceutical companies & I have participated in a several of them (the clinical trials for Fentora was my favorite) I just finished one that was for a new medicine for opiate induced constipation. I checked with them prior to posting this and they said I could discuss it so long as I dis not mention names. Which is ironic cause the med didn't have a "name" just a long number. Anyway it is a drug that however it does what it does it blocks the effects of the opiates in the bowels & colon & the rest of the digestive system. So your gastro intestinal system doesn't realize you are on opiates. After about two weeks or so my bowels straightened up & acted just like they were suppose to. I was as regular as I was before I started taking narcotic pain relievers. It was really nice, no more measures to fight constipation, it was no longer an issue. Back to "normal". I really hated to see that study come to an end. If all goes well they should have it ready & on the market like some time next spring they said. If it makes it & works half as good for others as it did for me it will be a godsend for a lot of people especially those who are on high doses of opiates. Of course who knows what the side effects will be with it (I should but I can't recall reading anything in particular). So anyhow if this concerns you be on the lookout for this "wonder drug" next year & I'll definately post it if it comes to pass. Good day to all.
after the last episode i had a few months ago, i keep an enema in the cabinet, just incase. That was the most miserable day in my life, i ended up like pulling both my hamstrings from pushing so hard, lol. Its funny how opiates fuck with your body, lol, to much and you cant shit, not enough and you cant stop shitting. Things that make you go hmmmmmm......
Yeah I know what you mean. Been plugged up so long you welcome the idea of having diarrhea and on the other hand after a couple rounds of that your ready for the constipation to set in. There's just no happy median in that battle. Good luck all.
I am lucky with this problem. I have a window in the morning from when I wake up until 11:00 am (when I take my first Suboxone dose) when I can do my business, so to speak.
Bowel Regimen: All patients on opioids should be on a stepped BOWEL REGIMEN: 1. → Senna + docusate (Senokot S) 1-2 tabs twice daily or → MOM 30-60 cc twice to three times daily or → Lactulose 30-60 cc twice to three times daily or → PEG solution (Miralax) 1-4 T daily 2. Double dose or high dose stimulant + osmotic 3. Methylnatrexone (Relistor) for unresponsive opioid bowel while continuing conventional bowel management preparations (this is normally a short-term intervention). a. Methylnatrexone is a Mu opioid antagonist that does NOT cross BBB b. Dosing: 8 mg (81-135lb); 12 mg (> 135 lb) or 0.15 mg/kg sc every other day or as needed not to exceed q24hr
