Used methadone liquid recreationally yesterday and only yesterday and am just wondering when can I get high off oxy's? I only use OC's 3 times a week max and am hoping I can use today. If I use oxy 24hrs after methadone will it work to the fullest or will the methadone still block opiates? I had about 25ml of methadone yesterday and am hoping to use 10-20mg oxy today. Any help is appreciated. Peace&Love