5-MeO-DMT

Discussion in 'Synthetic Drugs' started by TokeTrip, Sep 2, 2005.

  1. Phrensied Rabbits

    Phrensied Rabbits Member

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    There's something I'm wondering.
    Why is it that some DMT extraction recipes use an organic solvent to remove the alkaloids from solution, instead of letting the water evaporate?
    Probably purity, huh?
    So, this step isn't really necessary?
    It seems kind of complicated and expensive compared to simpler techniques used just to get the alkaloids out of the plant quickly and easily.

    Did my question make any sense?
     
  2. Psylence

    Psylence Member

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    I think it is because of solubility.....also naptha dries alot faster.
     
  3. Phrensied Rabbits

    Phrensied Rabbits Member

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    Well, that's for removing fatty materials and oils, as far as I understand.
    Sometimes there's a step after that to bring the ph way up
    and use an organic solvent to extract the alkaloids.
    Probably just to avoid getting all the crud left over in the water
    contaminating the final product.

    I'm wondering if anybody's used a simple method of using, like, lemon juice or something and stopped there~ maybe using a naptha treatment, too.
    What kind of calculation of dosage would you do with that?
    Kind of tricky to my mind at the moment.
    I'll keep reading some more <(^_^<)

    Grouve on
    Salaam Aleikom
     
  4. Phrensied Rabbits

    Phrensied Rabbits Member

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    You know what, that was a stupid question.
    I shame myself,~
     
  5. hippypaul

    hippypaul Hip Forums Supporter HipForums Supporter

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    Very well said and O so true. It also so important these days to know what your getting. The days of the chemist who was making it for the improvement of humankind are a ways in the past. Organic Chemistry is hard to do in your basement. It takes 5 to 7 thousand just to get basic lab gear. Then you have to start from scratch to avoid any of the feds "red flag" precursors.
     
  6. Psylence

    Psylence Member

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    \



    SWIM got some lab glass like this.....meet some new people...if you are attractive it really works. Meet a girl/guy tell him/her a fake name, hang out, get high, have sex, see movies, walk the dog, whatever. Tell him/her you are a chem student and that you broke a 2000ml RB flask in lab and that you need to replace is before the professor finds out, tell him/her to get an ebay account,(works better if they alredy have one, just bring up Ebay when you meet them) Then just bid on all the stuff you need, get it shipped to his/her house. Once you have your lab tell him/her a crazy story about why you have to move back to bumfucked, montanna....and then you just dip out with a lab to where you are really moving. Make no friends and cook your stuff, go back home and give it all away!!!!!!!!!!!!!!!!
     
  7. Phrensied Rabbits

    Phrensied Rabbits Member

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    Uhm, you know-
    I'm really confused about this.
    hehe [​IMG]

    What exactly is the purpose of putting the alkaloids in
    free-base form when you're extracting them?
    I don't get it,~ sorry [​IMG]
     
  8. hippypaul

    hippypaul Hip Forums Supporter HipForums Supporter

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    Without going into unwise detail, a careful reading of the following should answer your question.

    Phenethylamine is an alkaloid and monoamine. In the human brain, it is discussed as a putative neuromodulator or neurotransmitter. In nature phenethylamine is synthesized from the amino acid phenylalanine by enzymatic decarboxylation. It is also found in many foods, especially after microbial fermentation, e.g. in chocolate. Phenethylamine is a colorless liquid that forms a solid carbonate salt with carbon dioxide (CO2) upon exposure to air. Phenethylamine from food (e.g. chocolate) has been discussed to have psychoactive effects. However, it is quickly metabolized by the enzyme MAO-B so that significant concentrations do not reach the brain.

    Substituted phenethylamines are a broad and diverse class of compounds that include alkaloids, neurotransmitters, hormone, stimulants, hallucinogens, entactogens, anorectics, bronchodilators, and antidepressants.

    The phenethylamine structure can also be found as part of more complex ring systems like in the ergoline system of LSD or the morphinan system of morphine.





    Substituted phenethylamines

    General structure of phenethylamines and amphetamines (see the table below).Substituted phenethylamines carry additional chemical modifications at the phenyl ring, the sidechain, or the amino group:

    Amphetamines are phenethylamines carrying an alpha-methyl (α-CH3) group at the sidechain carbon atom next to the amino group.
    Catecholamines are phenethylamines carrying two hydroxy groups in positions 3 and 4 of the phenyl ring. Examples are the hormones and neurotransmitters dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline).
    The aromatic amino acids phenylalanine and tyrosine are phenethylamines carrying a carboxyl group (COOH) in alpha position.

    Pharmacology
    Many substituted phenethylamines are pharmacologically active drugs due to their similarity to the monoamine neurotransmitters:

    Stimulants like the plant alkaloids ephedrine and cathinone and the synthetic drugs amphetamine (speed, benzedrine) and methylphenidate.
    Hallucinogens like the plant alkaloid mescaline and the synthetic drug 2C-B.
    Empathogen like MDMA (ecstasy) and MDA.
    Anorectics like phentermine, fenfluramine, and amphetamine.
    Bronchodilators like salbutamol and ephedrine.
     
  9. Phrensied Rabbits

    Phrensied Rabbits Member

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    I think there's something wrong when everything's explained by that...
    wow, thanks man.
     
  10. hippypaul

    hippypaul Hip Forums Supporter HipForums Supporter

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    OK try this



    At this point, the process has yielded free base. In this state, the substance is quite unstable and not suitable for storage. A judgment as to the purity of the product is therefore needed in quick order, because which method of further processing to use is dependent upon the purity of the product. The purity will depend on the amount of iso- product that is present.



    Is that any more help - all of the above by the way is from my collage organic chem. text and in no way is intended for anything other than informational purposes.
     
  11. Phrensied Rabbits

    Phrensied Rabbits Member

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    Actually, I was serious when I said that'd helped.
    What I was wondering was whyyou had to put it in freebase to smoke it, but then I got bored and decided to go try to vaporize some salt to find out. After a couple minutes I just started feeling like an idiot for not having enough sense to realize wht it took me that little experiment to realize.

    Thanks for the technicals, though.
    Always helps,~
    Grouve on
     
  12. Phrensied Rabbits

    Phrensied Rabbits Member

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    I'm doubting the scientific nature of my little experiment, as I've brought up the subject with a couple apparently fairly experienced persons in the field of extraction and usage, and they seem to have a bit of confusion too about the smoking of dmt before putting it in freebase form. I'm not sure about it, because it's in salt form, but ~ is it possible?

    Of course, I'm in no position to try it out at the moment <(^_^<)
     

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