Smokeing has allways helpd me , but yes their are some who it wont help For me personally, i think ganja and some anti depressents would be the way to go ( in therory) Pot really helps on my manic days and dose a lil bit for the depressed days makes me feel much more comfortable in my own skin.Booze however is a no go ... I start to feel crazy like i suddenly became evil becuz i got drunk....needless to say i dont drink much these days