drugs of the future...

thats not true. im a firm believer that ANY drug can be used beneficially. its all about self control. some drugs you need more self control than others. speed is amazing when you need to get a whole rack of shit done in a short amount of time. opiates are great for when youve had a stressful day and just wanna relax and sleep. its all about your personality which determines wether they can be beneficial or not. im not one of the people who can use opiates for good since i have no self control over that but i know people who can.

 

Babylon has always been doomed my friend. But as soon as one system falls there's already another to take its place. It may be better, or by definition "good" for the people, however that transitional period never lasts long. It's a never ending cycle that has plagued humanity sense we've developed the ability to interpret thought.

Oh and in regards to what drug I think will be big then. Well, if things continue to go the way they are right now (at least in the States) Ecstasy will only become more widely/heavily used. It's sad if you ask me, because if you look at what a societies "drug" habits are you can tell a lot about the people as a whole...as we all know ecstasy is a euphoric drug that does not really encourage much thought (if used in the right setting, it has the ability to do good for relationships). People just don't care anymore, they don't want to think for themselves, they are fine with being told what to think so long as they can go about their daily lives consuming and living in an ignorant bliss to what goes on in the world. So, America "Go stupid, go dumb!!"

(I have respect for pure MDMA and it's ability to resolve certain emotional issues, or make them evident, however I'd be willing to bet that well over 90% of ecstasy these days is cut and mainly with speed at that)

 

hmm ive been thinkin bout this recently. i figure with partyish drugs like xtc and ketamine have only two fates. either a new explosion in use in them will occur thanks to the likes of some new rc's becoming popularised (2c-x's) and an entirely new group of drug users could be created, or they will simply be forgotten about along with rave culture. never really going off the market, but deffinitly no where near the popularity they have now.
as for psychedelics i see them most likely growing in popularity through the now more mainstream mushrooms, and with a large new wave of psychedelic rc's just waiting to be introduced to the market, i think there is deffinitly a chance of something big happening with them in the next few years.
i also imagine prescription drug abuse, perticulary opiates and benzo's, will rise steadily untill they are inevitably made schedule 1. well maybe not by being made a schedule one but, kinda like what happened to barbituates, newer stronger and cheaper prescription drugs will be made and make the old ones unappealing and less likely to be prescribed.
i see stimulants coasting about at their current level of popularity, maybing going down a bit as the next wave of abusers will have limitless supplies to non stimulant add meds, instead of the nostop supply of adderalls today. i think meth abuse will rise for a short period of time when it becomes more introduced to the north east, but will then peak and become like a cocaine like drug. and lastly i see heroin coasting as well, probably going down very slowly. i dont see it ever becoming really big again, but who knows

 

Yeah, I think shrooms are gonna get really popular.

 

They always have been

 

the real future of drugs: psychedelic proteins. right now the technology is new, expensive, and completely medicinal (protein therapeutics for treating illness/disease).

i just started my biotechnology class recently so i might not exactly understand what im talking about, but i know G protein-coupled receptors (GPCRs) are directly related to 5-HT2A & 5-HT receptors (the mechanism of action for hallucinogens).

simple proteins can be produced through synthesis, but the complex ones can only be produced by living organisms (think yeast or fermentation) which would require genetic modification of the organism's DNA. Would someone with knowledge on the subject expand on my hypothesis or explain why im wrong? im only assuming that there’s proteins undiscovered that’ll have psychedelic effects.

 

err.. that might be plausible for some intense treatment for terminal illness.. but coaxing a person's brain to create proteine structures that will then cause a psychedelic experience? id say that would never happen.. and woul dbe incredibly expensive and dangerous unless controlled.

G-protein-coupled receptors are protein structures that respond to hormones and other organic chemicals floating around cells. G proteine-coupled receptors are involved in most drug interactions. Other types of receptors include ion gates.

The former gets a signal chemical and then it changes shape, altering the internal function of the cell.
the latter gets a signal chemical and then opens, allowing chemicals to flow in and out of the cell.

Theyre all proteins. every functional part of the body is protein.

In order to use proteins to influence these functions, you have two options:
create a protein that interacts with existing proteins
or create a protein that provides a new way for chemicals to interact.

The former option is unlikely because yo uwould need the proteins to reach their site of action, but when we ingest proteins they are broken down into amino acids. Otherwise, they would start interacting with all of the cells in your body, tangling up with other proteins and causing possible malfunction. A protein so specific that it only interacted with specific brain areas would be rather complicated.. and thus more likely to physically disrupt other processes, or be sensed by the body as foreign.

the latter option, to introduce new protein forms.. would require specific placement of these protein forms. If we want a psychedelic experience, we would need these proteins to form on th neurons in our brain. So we would effectively need to coax only the neurons to produce a new protein that would create an extra function. since we dont actually know enough about the brain to develop a new function that we know would not simply disrupt all other functions, this option is entirely dangerous and almost destined to lead to pain and suffering in test subjects.
And when we consider what it would mean to coax cells into producing new proteins.. its almost like giving someone a virus.. and if you gave them some virus it could mutate and lead to new brain diseases that could spread

but its good that you are considering possibilities!

 

self control comes at a price. But there are different types of self control. There is teh self control where we avoid things we want to do, and there is self control where we learn to like things that are good for us.

Most people with good healthy lives who would be considered to have good self control would fall under teh latter category.


But the sort of self control that people use to avoid the things they want leads to stress, which people usually release late at night or at the end of the week at a party.

You say that opiates can be good to those with high self-control. They are good because they can relieve stress. But if you start generating amounts of stress necessarily in order to counteract your necessary urges for opiates (it occurs to everyone to different degrees), you will desire the opiates more and then require more self control to prevent using them and then generate more stress, etc.
The people who use opiates but not too much, likely take other drugs that they use as their fundamental de-stressor.

Opiates can only ever be good to people who are in pain. Otherwise they will always lead to pain

if you want to relax, smoke a cone.

Thats not to say 100% sure no one can take opiates for good purpose.. but its to say that no one can 100% take opiates in a good way. The negatives may simply be dealwithable in that person's routine, which in itself might be rather different to most people's

 

i remember my professor discussing something about the future of therapeutic drugs. he mentioned the idea of personalized medicines, why not personalized psychedelics (going back to my cocktail pill idea)? with the mapping of the human genome and increasing knowledge in pharmacology its very possible. imagine this drug deal:

hey, whats up, joe sent me to come see you.
what do you need?
im going to this concert, lots of bitches and lasers.
alright, let me get a DNA sample.
.....
i got just the thing for you. this compound makes you honry and this will give you visuals. according to your genetic code, you're deficient in an enzyme to metabolize compound A, so i will increase the dose and include a supplement of vitamin X. this pill has been designed to be active for 5 hours, it will begin with intense visuals then end with a body high you can enjoy with some bitches. in the morning take this pill, it'll reduce much of the negative effects from the night before.
cool, thanks.
....
wait, what is this?... you have the mark.
wtf?
the mark, its in your code... i have this compound, it's called "heaven", and those who are able to experience it are said to be blessed by God. it's only active in one in a million people... and you are one of them.
cool, ill take 10 of them.