I was a big MDMA lover years ago, but then came times, when I couldn“t get pure stuff any more (from controlled resources). Then I came along Methylone, and even though I can get good MDMA without any problem now, Methylone is my favorite. And I love to mix it with 2C-E.
I'd try to extract psilocin, or psilocybin out of mushrooms. If they sold that shit around here, I would buy it, just so I didn't have to eat all that fungal matter.
that's what I've said; do an extraction w/ methanol, glacial acetic acid, and run that shit through a column of silica, using a gradient of EtOAc:MeOH. *emeril voice* bam. you'll be left with reasonably pure, white psilocin crystals.
^^Extracting mushrooms would be simple enough, but unless you live where alot of them grow wild it would probably be alot cheaper just to buy a gram of 4ho-whatever.
it would probably be a lot harder just to find a gram of 4-HO-DMT, in its pure form. it would be easier to go look in pastures for "blue staining" mushrooms, because trade winds/hurricanes carry spores all over the planet, and they readily grow in warm, humid areas
depends on the route of synthesis (as I have found out); disubstituting tryptamine can be a tricky affair, when adding an acid (to regulate pH) to a formaldehyde/Sodium cyanoborohydride in methanol solution. Reduction takes place, but the acid tends to make the amine cyclize, and attach itself to the pyrrole ring. Of course, there are several methods for synthing DMT; the easiest by far starts from tryptophol, using dimethylamine as the reagent. GHB, Meth, and Cat are all fairly easy to synth, probably without any practice needed. I'd say meth and (surprised noone mentioned it) U4euh (methylaminorex) are easier to synth than dmt.