Huh...I haven't come back to this. I did end up watching season 9 of Scrubs and actually dug it. I really liked the doctor JD called "Jo."
Hannibal comes to mind first. Started off with a really good first season, loved the concept, love the actor that played Hannibal, but boy did it get freakin weird in a lame way in season 2 and 3. Heroes too, awesome 1st season, have watched the first season about 6 times, but by the 4th season was unwatchable
As far as shows jumping the shark, I nominate Dexter. Seasons 1 - 4 were really good, especially season 4 with John Lithgow...he was excellent in it...but it just all went downhill after that and the last season and series finale was probably the worst of any show i've seen. Just. So. Bad
Never really watched Happy Days but i loved the intro so i'd watch it then change the channel to whatever else was on
There’s been talk of a Married with Children reboot – I hope it doesn’t happen no one could replace Ed O’Neill, Katey Sagal, Christina Applegate, David Faustino, and of course Amanda Bearse as Marcy (who btw was really hot as Amy in the movie Fright Night) for those of you who remember.